Miller School of Medicine researchers have found that the age of a donor mouse affects the ability of its mesenchymal stem cells (MSCs) to repair damage to the lungs caused by pulmonary fibrosis. Their laboratory study, published recently in Translational Research, has important implications for clinical stem cell treatments in older patients with damaged and scarred lung tissue caused by smoking or other conditions.
A new study from the University of Miami’s Interdisciplinary Stem Cell Institute has found that the sympathetic nervous system plays a vital role in heart regeneration. Prior to this study, scientists were aware of the potential for cardiac regeneration in the human neonatal period, but the factors involved in this process remained unknown.
A new study from the University of Miami's Interdisciplinary Stem Cell Institute (ISCI) demonstrates the involvement of cKit-expressing progenitors in the formation of cardiomyocytes – heart muscle cells. The findings help resolve a long-standing controversy regarding the role of cKit in the heart.